|
KMID : 1123920090230030695
|
|
Korean Journal of Oriental Physiology and Pathology
2009 Volume.23 No. 3 p.695 ~ p.699
|
|
|
Prevention of Photoaging and Wrinkle Formation in Hairless Mice by Korean Red Gnseng and Fagopyrum Esculentum Extract Mixture
|
|
Kim Dae-Sung
Jeon Byoung-Kook
Choi Mi-Eun
Mun Yeun-Ja
Park Seok-Don
Woo Won-Hong
|
|
|
Abstract
|
|
|
|
UV irradiation causes skin-aging involving coarse wrinkles, thickening, dyspigmentation, and rough skin surface. This study was carried out to develop health & functional food by using Korean red ginsneg and Fagopyrum esculentum extract mixture (RGFE) for prevention of skin wrinkles. The RGFE-treated group showed the more effective collagenase inhibition rate than the red ginseng (RG)-treated group. To investigate photo protective effects of RGFE on UV-induced damaged skin, SKH hairless male mice were orally administerd RGFE and regional treatment and irradiated with UV for up to 8 weeks. In RGFE-treated group, better skin, and less wrinkle formation were observed compared with UV group. Epidermal thickness of hairless mouse was significantly decreased in RGFE, RG, and Fagopyrum esculentum (FE) groups compared with UV group. These results demonstrate RGFE have photo-protective effects on UV-damaged hairless mouse skin.
|
|
|
KEYWORD
|
|
|
anti-wrinkle, collagenase, Korean red ginseng, fagopyrum esculentum
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|